The Isuzu Pickups fabricated their admission in 2006, and the aggregation cab archetypal was bound nominated as "Truck of the Year" by two altered magazines, "Truck of Texas" and "Four Wheeler of the Year." IntelliChoice called the 2006 models a "Smart Choice" in ten altered ownership-cost categories, and singled out the 2006 i-280 Extended Cab S as the "Top Winner" in its chic for everyman adjustment costs.
For 2007, the i-280 Extended Cab 4x2 becomes the i-290, and the i-350 Aggregation Cab 4x4 is renamed the i-370. Trim levels abide unchanged: the i-290 is accessible in abject S trim, with Preferred Equipment, LS and Luxury bales optional, and the i-370 is accessible in LS or alternative Limited trim. Both cartage get larger, added able engines. The changes for the 2007 archetypal year:
- 2.9-liter inline four-cylinder engine replaces 2.8-liter, increasing horsepower to 185 hp (vs. 175) and torque to 190 ft.-lbs. (vs. 185)
- 3.7-liter inline five-cylinder engine replaces 3.5-liter, increasing horsepower to 242 hp (from 220) and torque to 242 ft.-lbs. (vs. 225)
- Base i-290 S available with automatic transmission as well as manual transmission
- Tire Pressure Monitoring System added as standard equipment on all models
- 3.73 rear axle ratio added on manual transmission models (replaces 3.42 rear axle ratio)
- Towing capacity of manual transmission models increases from 1,700 to 2,100 lbs.
- Pacific Blue exterior color added
- Deep Crimson Metallic replaces Red Rock Metallic exterior color
- Bering Blue Metallic replaces Adriatic Blue Metallic exterior color
- Ebony interior trim replaces Very Dark Pewter (LS, Luxury and Limited)
- Chrome accents added to HVAC lever, gauges, and speaker surrounds (LS, Luxury and Limited)
- Chrome accents to be added mid-year to interior door handles and locks (LS, Luxury and Limited
- Map lights deleted from inside rear view mirror